How Long Does Ketamine Last for Depression

Have you ever been through ketamine therapy? If yes, you must be aware of its consequences and the impacts that take you towards a healthy lifestyle.
Many people are afraid of availing of ketamine therapy. They might be curious about: how long does ketamine last for depression. Let’s find out about the query together.
Approximately 264 million people have this mental disease and are still struggling to overcome it.
If you are suffering from depression and struggling to find relief from it, you must try ketamine treatment.

So, why not ATLANTIS INTEGRATIVE MEDICINE & PSYCHIATRY WELLNESS CENTER? We are here to treat your depression through ketamine therapy in an efficient way.

What is Ketamine Therapy?

Ketamine therapy is a treatment method that uses low doses of ketamine to handle numerous mental health conditions. These are included as:

  • Depression
  • Anxiety Disorders
  • Post-Traumatic Stress Disorder (PTSD)

Furthermore, it was approved in 1970 by the U.S. Food and Drug Administration. In the meantime, it is used for surgery, anti-anxiety effects, and rapid-acting antidepressants.
Afterward, doctors then started observing it as a treatment for depression and anxiety.
For ketamine therapy and more information, you may contact us!

Our Ketamine Treatment Options

1.Spravato Esketamine Nasal Spray

The only FDA-approved nasal spray for grown-ups to treat major depressive disorder (MDD).
Furthermore, esketamine spravato has been clinically proven to benefit patients in a variety of ways:

  • Stabilizing the mood
  • Lowering the severity of depression
  • Delaying the onset of symptoms
  • Reduction in suicidal thoughts

Our healthcare professionals at ATLANTIS will instruct you about the use of the nasal spray device.  The dosage and treatment plan are decided by the severity of your illness and response to treatment.

2.Ketamine Infusion Therapy

Ketamine infusion therapy can help with a variety of mental health problems, but it is most commonly used for treatment-resistant depression, a type of major depressive disorder. Ketamine infusion therapy benefits the individuals as:

  • Activates neurons by connecting them to NMDA receptors
  • Mind calmness
  • Reduce the desire for narcotic painkillers
  • It doesn’t affect blood pressure and breathing

Once the ketamine begins to work, our mental health therapists will assist you in replacing adverse emotions with positive ones. Ketamine can induce beneficial changes in the brain.

 Ketamine Treatment for Depression

While taking the ketamine treatment, the very first question that comes to people’s mind is:  how fast does ketamine injection work? So, Ketamine injection takes seconds to minutes to treat depression.Furthermore, you’ll be amazed to know that ketamine is not only used as a pain killer; it has a lot of other functions. The most probable one is depression and anxiety treatment.
According to the World Health Organization, it is the main source of numerous mental disorders all over the world.

Benefits of Ketamine Therapy

Ketamine is a central topic to discuss nowadays due to the following reasons:

  • The first thing that makes the ketamine therapy process exceptional from the other is its rapid action.
  • Other medications take weeks or even months to bring the results; ketamine helps to lessen the depression symptoms in almost no time.
  • If the patient’s symptoms are mild to moderate, he might feel well after a few hours of his first session.
  • It could take a few days or weeks for the patient to experience substantial relief from severe symptoms.
  • It is an appropriate option for non-compliant patients, particularly older ones who forget to take their medicine at a given time.

How Long Does Ketamine Last for Depression- Few Aspects to Consider


The relief from the pain entirely depends upon the quantity of the dosage you are giving to the patient. The average dosage for depression ranges from 0.5 to 2 mg/kg. This dosage is given slowly, and it takes up to 30 minutes to work.

2.Frequency Of Use

people use opioids for the rapid relief of pain. In contrast, it is as much as effective as they think. So, they move towards other options, such as ketamine. It is considered the best option for ketamine recovery along with depression treatment.

3.Method Of Administration

There are two methods for ketamine administration:

  1. Intravenous (IV)
  2. intramuscular (IM)

4.Presence Of Other Illnesses

If a patient suffers from other diseases, this will also affect the extent of ketamine treatment. For example, a patient who suffers from depression and chronic pain may take longer for the ketamine treatment to be effective.

Side Effects of Ketamine Infusion for Pain

Along with its desirable effects, a medicine may cause some undesirable effects.
Minor side effects occur; if they do occur, they may need medical consideration.
Consult with your doctor or nurse instantly if any of the following side effects occur:

Incidence not known

  • Bloody or cloudy urine
  • blurred or change in vision
  • chest pain, discomfort, or tightness
  • confusion
  • cough
  • dizziness
  • bluish lips or skin
  • burning while urinating
  • painful urination
  • difficulty with swallowing

How Long Does Ketamine Nasal Spray Last?

Ketamine nasal spray, specifically (Spravato), offers an encouraging option for individuals with treatment-resistant depression.
Here are the key points about its extent and effects:

  • Unlike most oral antidepressants, ketamine works quickly.
  • People may observe relief in symptoms within just a few hours after supervision.
  • The effects of ketamine nasal spray can last for several days, making it advantageous for those seeking rapid relief.
  • Patients receive nasal puffs of ketamine once or twice a week in a doctor’s office or hospital setting.

How Long Does Nausea Last After Ketamine?

Patients receiving a ketamine infusion may experience dizziness or nausea.
The duration of nausea varies depending on the patient’s response to ketamine and the dose administered.
Higher doses can cause a slight floaty feeling that lasts for several hours after treatment.
If nausea persists, it is critical to consult with a ketamine specialist to explore appropriate medication.

How Long Does Ketamine Stay in Your System?

These factors that affect ketamine stay are stated below.
Several factors determine how long ketamine takes to last in your body:

  • Those who have a faster metabolism in their body will be able to eliminate ketamine from their body.
  • If a person is well-hydrated, there is a high likelihood that most of the ketamine is removed via urine.
  • Individuals who have a higher weight will be able to swiftly eliminate the ketamine drug from their bodies as compared with those who have smaller body mass.
  • Naturally, the excess ketamine intake makes the body stiffer when getting rid of it.

Let’s Recap

How long does ketamine last for depression? The effect of ketamine for depression treatment varies due to some factors. Likewise, the duration of ketamine for depression remains from days to weeks, depending on the condition of the patient.

These factors that disturb the duration of ketamine are:

  • The amount or quantity
  • Frequency of ketamine dosage
  • The tolerance of individuals

If you or any of your family members are coping with the issue of depression and want to avail of ketamine therapy, you may rely on us.

Frequently Asked Questions

How long does ketamine pain relief last?

The most common session for the ketamine treatment is the 40-minute. Its effect is sustained in the body for a few hours to days.

How many ketamine infusions for chronic pain?

Modern research shows that ketamine is beneficial in the treatment of chronic pain conditions, mainly those with a neuropathic component.

How long does ketamine take to work?

Ketamine is a fast-acting antidepressant that can lessen depressive symptoms in a few hours. Moreover, the duration varies and depends upon the persistence of the patient and the extent to which they hold it in their body.

How fast does ketamine work for anxiety?

The ketamine takes 2-6 weeks to work for the anxiety.

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